Perlapine
货号：
17756-1mg 基本售价：
630.0 元 规格：
1 mg
产品信息
概述| 货号 | 17756-1mg |
| 描述 | Perlapine is an atypical neuroleptic that blocks dopamine and serotonin (5-HT) receptors (Kis = 60, 30, and 30 nM for D2, D4, and 5-HT2A, respectively).1 Perlapine is also an agonist for hM3Dq, a designer receptor exclusively activated by designer drugs (DREADD) derived from the human muscarinic acetylcholine M3 receptor that activates neuronal firing.2 Perlapine displays >10,000-fold selectivity for hM3Dq over hM3.2 |
| 别名 | 6-(4-Methyl-1-piperazinyl)morphanthridine;NSC 291840; |
性能| 供应商 | Cayman |
| 应用文献 |
1.Seeman, P.,Corbett, R., and Van Tol, H.H. Atypical neuroleptics have low affinity for dopamine D2 receptors or are selective for D4 receptors. Neuropsychopharmacology 16(2), 93-110 (1997).
2.Chen, X.,Choo, H.,Huang, X.P., et al. The first structure-activity relationship studies for designer receptors exclusively activated by designer drugs. ACS Chem.Neurosci. 6(3), 476-484 (2015).
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| 运输条件 | Wet ice in continental US; may vary elsewhere |
| 存放说明 | -20 |
| 纯度 | ≥98% |
| 计算分子量 | 291.4 |
| 分子式 | C19H21N3 |
| CAS号 | 28432 |
| 稳定性 | ≥ 2 years |
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