Perindoprilat
货号：
17574-500ug 基本售价：
630.0 元 规格：
500 ug
产品信息
概述| 货号 | 17574-500ug |
| 描述 | Perindoprilat is the active metabolite of perindopril, an inhibitor of angiotensin converting enzyme (ACE) that has efficacy against hypertension.1 Perindoprilat specifically and competitively inhibits ACE in vitro with IC50 values ranging between 1.5 and 3.2 nM. Elimination of perindoprilat is decreased in the elderly and in patients with heart or renal failure.1,2,3 |
| 别名 | S-9780; |
性能| 供应商 | Cayman |
| 应用文献 |
1.Wang, J.g.,Pimenta, E., and Chwallek, F. Comparative review of the blood pressure-lowering and cardiovascular benefits of telmisartan and perindopril. Vascular Health and Risk Management 10, 189-200 (2014).
2.Sennesael, J.,Ali, A.,Sweny, P., et al. The pharmacokinetics of perindopril and its effects of serum angiotensin converting enzyme activity in hypertensive patients with chronic renal failure. Br.J.Clin.Pharmac. 33, 93-99 (1992).
3.Parker, E.,Aarons, L.,Rowland, M., et al. The pharmacokinetics of perindoprilat in normal volunteers and patients: Influence of age and disease state. European Journal of Pharmaceutical Sciences 26(1), 104-113 (2005).
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| 运输条件 | Room temperature in continental US; may vary elsewhere |
| 存放说明 | -20 |
| 纯度 | ≥95% |
| 计算分子量 | 340.4 |
| 分子式 | C17H28N2O5 |
| CAS号 | 95153-31-4 |
| 稳定性 | ≥ 2 years |
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