11β-13,14-dihydro-15-keto Prostaglandin F2α
货号：
16540-50ug 基本售价：
630.0 元 规格：
50 ug
产品信息
概述| 货号 | 16540-50ug |
| 描述 | 11β-13,14-dihydro-15-keto Prostaglandin F2α (11β-13,14-dihydro-15-keto PGF2α) is a metabolite of Prostaglandin D2(PGD2) in the 15-hydroxy PGDH pathway.1,2 Infusion or inhalation of tritiated PGD2 in normal males results in the appearance of peak levels of both 11β-PGF2α, as the immediate product, and 11β-13,14-dihydro-15-keto PGF2α in the plasma within 10 minutes.1 Homogenates of human lung metabolize PGD2 first to 11β-PGF2α and then to 11β-15-keto-PGF2α in the presence of NAD+, but no 11β-13,14-dihydro-15-keto PGF2α.2 Guinea pig liver and kidney homogenates metabolize PGD2 to 11β-13,14-dihydro-15-keto PGF2α,via11β-PGF2α, in the presence of NAD+ and NADP+.2 |
| 别名 | 11β-13,14-dihydro-15-keto PGF2α;11-epi 13,14-dihydro-15-keto PGF2α; |
性能| 供应商 | Cayman |
| 应用文献 |
1.Robinson, C.,Hardy, C.C. and Holgate, S.T. The metabolism of prostaglandin D2 after inhalation or intravenous infusion in normal men. Biochimica et Biophysica Acta 963, 151-161 (1988).
2.Robinson, C.,Herbert, C.A.,Bedwell, S., et al. The metabolism of prostaglandin D2. Evidence for the sequential conversion by NADPH and NAD+ dependent pathways. Biochemical Pharmacology 38(19), 3267-3271 (1989).
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| 运输条件 | Wet ice in continental US; may vary elsewhere |
| 存放说明 | -20 |
| 纯度 | ≥95% |
| 计算分子量 | 354.5 |
| 分子式 | C20H34O5 |
| CAS号 | 107615-77-0 |
| 稳定性 | ≥ 1 year |
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