Guanethidine (sulfate)
货号：
16217-100mg 基本售价：
630.0 元 规格：
100 mg
产品信息
概述| 货号 | 16217-100mg |
| 描述 | Guanethidine is an antihypertensive compound that competes with norepinephrine for transport into presynaptic terminals of adrenergic neurons by the norepinephrine transporter.1 Once guanethidine has entered the nerve, it becomes concentrated in synaptic vesicles, depleting endogenous norepinephrine, and thus, reducing the release of norepinephrine in response to action potentials.1 Guanethidine’s actions are restricted to peripheral nerve terminals because its basic guanidine group does not allow passage through the blood brain barrier.1 Its use has been explored in the relief of chronic pain caused by complex regional pain syndrome.2 |
性能| 供应商 | Cayman |
| 应用文献 |
1.Gerber, J.G.,Freed, C.R. and Nies, A.S. Antihypertensive pharmacology. West.J.Med. 132(5), 430-439 (1980).
2.Livingstone, J.A. and Atkins, R.M. Intravenous regional guanethidine blockade in the treatment of post-traumatic complex regional pain syndrome type 1 (algodystrophy) of the hand. J.Bone Joint Surg.Br. 84(3), 380-386 (2002).
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| 运输条件 | Room temperature in continental US; may vary elsewhere |
| 存放说明 | -20 |
| 纯度 | ≥95% |
| 计算分子量 | 296.4 |
| 分子式 | C10H22N4 • H2SO4 |
| CAS号 | 645-43-2 |
| 稳定性 | ≥ 2 years |
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