Zolmitriptan
货号：
15871-5mg 基本售价：
630.0 元 规格：
5 mg
产品信息
概述| 货号 | 15871-5mg |
| 描述 | Zolmitriptan is a triptan that acts as an agonist of the serotonin (5-HT; Item No. 14332) receptors 5-HT1B and 5-HT1D(Kis = 2.2 and 0.92 nM, respectively).1,2 Through this action, zolmitriptan inhibits cAMP formation in blood vessels, resulting in vessel constriction.1,2 Triptans, including zolmitriptan, are considered first-line therapy for moderate to severe migraine.3 |
| 别名 | BW 311C90;Zomig®; |
性能| 供应商 | Cayman |
| 应用文献 |
1.Perez, M.,Fourrier, C.,Sigogneau, I., et al. Synthesis and serotonergic activity of arylpiperazide derivatives of serotonin: Potent agonists for 5-HT1D receptors. Journal of Medicinal Chemistry 38(18), 3602-3607 (1995).
2.Wurch, T.,Palmier, C.,Colpaert, F.C., et al. Recombinant saphenous vein 5-HT1B receptors of the rabbit: Comparative pharmacology with human 5-HT1B receptors. British Journal of Pharmacology 120(1), 153-159 (1997).
3.Gilmore, B. and Michael, M. Treatment of acute migraine headache. American Family Physician 83(3), 271-280 (2011).
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| 运输条件 | Room temperature in continental US; may vary elsewhere |
| 存放说明 | -20 |
| 纯度 | ≥98% |
| 计算分子量 | 287.4 |
| 分子式 | C16H21N3O2 |
| CAS号 | 139264-17-8 |
| 稳定性 | ≥ 2 years |
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