Nelfinavir (mesylate)
货号：
15144-5mg 基本售价：
630.0 元 规格：
5 mg
产品信息
概述| 货号 | 15144-5mg |
| 描述 | Nelfinavir is an orally bioavailable inhibitor of the HIV-1 protease (Ki =2 nM) that is used in combination with HIV reverse transcriptase inhibitors for the treatment of HIV infection.1 Nelfinavir demonstrates anti-cancer activity, selectively preventing the growth of HER2-positive breast cancer cells in vitro by inhibiting Hsp90 (IC50 = 3.1 μM).2 |
| 别名 | AG-1343;Nelfin;Viracept; |
性能| 供应商 | Cayman |
| 应用文献 |
1.Kaldor, S.W.,Kalish, V.J.,Davies, J.F., II, et al. Viracept (nelfinavir mesylate, AG1343): A potent, orally bioavailable inhibitor of HIV-1 protease. Journal of Medicinal Chemistry 40(24), 3979-3985 (1997).
2.Shim, J.S.,Rao, R.,Beebe, K., et al. Selective inhibition of HER2-positive breast cancer cells by the HIV protease inhibitor nelfinavir. Journal of the National Cancer Institute 104(20), 1576-1590 (2012).
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| 运输条件 | Room temperature in continental US; may vary elsewhere |
| 存放说明 | -20 |
| 纯度 | ≥98% |
| 计算分子量 | 663.9 |
| 分子式 | C32H45N3O4S • CH3SO3H |
| CAS号 | 159989-65-8 |
| 稳定性 | ≥ 2 years |
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