Methylprednisolone
货号：
15013-500mg 基本售价：
630.0 元 规格：
500 mg
产品信息
概述| 货号 | 15013-500mg |
| 描述 | Prednisolone is the active metabolite of the synthetic corticosteroid prednisone, which is used to suppress inflammation and autoimmunity, as well as in other conditions.1 Methylprednisolone is a 6α-methyl derivative of prednisolone, a variation which reduces its binding to corticosteroid-binding globulin and increases penetration into target tissues.1 It alters gene expression, like prednisolone, through both the glucocorticoid and mineralocorticoid receptors.2 |
| 别名 | Medesone;Medrol;Noretona;NSC 19987;U 7532; |
性能| 供应商 | Cayman |
| 应用文献 |
1.Brownie, A.C. The metabolism of adrenal cortical steroids. The Adrenal Gland 2, 209-225 (1992).
2.Coghlan, M.J.,Kym, P.R.,Elmore, S.W., et al. Synthesis and characterization of non-steroidal ligands for the glucocorticoid receptor: Selective quinoline derivatives with prednisolone-equivalent functional activity. Journal of Medicinal Chemistry 44, 2879-2885 (2001).
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| 运输条件 | Wet ice in continental US; may vary elsewhere |
| 存放说明 | -20 |
| 纯度 | ≥98% |
| 计算分子量 | 374.5 |
| 分子式 | C22H30O5 |
| CAS号 | 83-43-2 |
| 稳定性 | ≥ 2 years |
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