FR900098 (sodium salt)
货号：
10012681-1mg 基本售价：
630.0 元 规格：
1 mg
产品信息
概述| 货号 | 10012681-1mg |
| 描述 | FR900098 is a derivative of fosmidomycin (Item No. 16000) that has antimalarial activity (IC50s = 170, 170, and 90 nM for HB3, A2, and Dd2 P. falciparum strains, respectively).1 FR900098 inhibits DOXP reductoisomerase, a key enzyme in the non-mevalonate pathway of isoprenoid biosynthesis, in vitro in a dose-dependent manner.1 FR900098 (>10 mg/kg, i.p.) eradicated P. vinckei parasites within four days in mice. |
性能| 供应商 | Cayman |
| 应用文献 |
1.Jomaa, H.,Wiener, J.,Sanderbrand, S., et al. Inhibitors of the nonmevalonate pathway of isoprenoid biosynthesis as antimalarial drugs. Science 285(5433), 1573-1576 (1999).
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| 运输条件 | Wet ice in continental US; may vary elsewhere |
| 存放说明 | -20 |
| 纯度 | ≥95% |
| 计算分子量 | 219.1 |
| 分子式 | C15H11NO5P • Na |
| CAS号 | 73226-73-0 |
| 稳定性 | ≥ 2 years |
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