Cordycepin
货号：
14426-10mg 基本售价：
616.0 元 规格：
10 mg
产品信息
概述| 货号 | 14426-10mg |
| 描述 | Cordycepin is a nucleoside analog found in C. sinensis that acts as a polyadenylation inhibitor when converted to cordycepin triphosphate, which inhibits ATP-dependent DNA and RNA synthesis.1 Cordycepin has a broad spectrum of biological activities, including anti-proliferative, pro-apoptotic, and anti-inflammatory effects.1,2,3 Cordycepin has been shown to reduce poly(A) tail length in mRNA at 10 μM and to activate AMPK kinase, leading to a reduction in mTOR signaling at 200 μM.1 |
| 别名 | 3-Deoxyadenosine;NSC 63984;NSC 401022; |
性能| 供应商 | Cayman |
| 应用文献 |
1.Wong, Y.Y.,Moon, A.,Duffin, R., et al. Cordycepin inhibits protein synthesis and cell adhesion through effects on signal transduction. The Journal of Biological Chemisty 285(4), 2610-2621 (2010).
2.Seo, M.J.,Kim, M.J.,Lee, H.H., et al. Effect of cordycepin on the expression of the inflammatory cytokines TNF-alpha, IL-6, and IL-17A in C57BL/6 mice. Journal of Microbiology and Biotechnology 23(2), 156-160 (2013).
3.He, W.,Zhang, M.F.,Ye, J., et al. Cordycepin induces apoptosis by enhancing JNK and p38 kinase activity and increasing the protein expression of Bcl-2 pro-apoptotic molecules. J.Zhejiang Unvi.Sci.B. 11(9), 654-660 (2010).
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| 运输条件 | Wet ice in continental US; may vary elsewhere |
| 存放说明 | -20 |
| 纯度 | ≥98% |
| 计算分子量 | 251.2 |
| 分子式 | C10H13N5O3 |
| CAS号 | 73-03-0 |
| 稳定性 | ≥ 2 years |
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