16-phenoxy tetranor Prostaglandin F2α methyl amide
货号：
10010562-500ug 基本售价：
602.0 元 规格：
500 ug
产品信息
概述| 货号 | 10010562-500ug |
| 描述 | Prostaglandin F2α(PGF2α) drives luteolysis and smooth muscle contraction by activating the FP receptor. Stable, lipophilic analogs of PGF2α are used to modulate luteolysis and treat glaucoma. 16-phenoxy tetranor PGF2α is a metabolically stable form of PGF2α containing a 16-phenoxy group at the ω-terminus. It binds to the FP receptor on ovine luteal cells with much greater affinity (440%) than PGF2α.1 16-phenoxy tetranor PGF2α methyl amide is a lipophilic analog of 16-phenoxy tetranor PGF2α. Methyl amides of PGs may serve as prodrugs, as they are hydrolyzed in certain tissues to generate the bioactive free acid. |
| 别名 | 16-phenoxy tetranor PGF2α methyl amide; |
性能| 供应商 | Cayman |
| 应用文献 |
1.Balapure, A.K.,Rexroad, C.E., Jr.,Kawada, K., et al. Structural requirements for prostaglandin analog interaction with the ovine corpus luteum prostaglandin F2α receptor. Biochemical Pharmacology 38, 2375-2381 (1989).
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| 运输条件 | Room temperature in continental US; may vary elsewhere |
| 存放说明 | -20 |
| 纯度 | ≥98% |
| 计算分子量 | 403.5 |
| 分子式 | C23H33NO5 |
| 稳定性 | ≥ 1 year |
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