CAY10683
货号：
15403-5mg 基本售价：
560.0 元 规格：
5 mg
产品信息
概述| 货号 | 15403-5mg |
| 描述 | CAY10683 is a potent histone deacetylase (HDAC) inhibitor isolated from the cyanobacterium Symploca.1 It inhibits HDAC2 and HDAC6 with IC50 values of 0.119 and 434 nM, respectively, and is without effect against HDAC4 (IC50 = >1,000 nM).1 CAY10683 inhibits the growth of HCT116 colon cancer cells and HuT-78 cutaneous T cell lymphoma cells (GI50 = 29.4 and 1.4 μM, respectively) more effectively than human dermal fibroblasts (GI50 = >100 μM).1 |
| 别名 | Santacruzamate A; |
性能| 供应商 | Cayman |
| 应用文献 |
1.Pavlik, C.M.,Wong, C.Y.B.,Ononye, S., et al. Santacruzamate A, a potent and selective histone deacetylase inhibitor from the Panamanian marine cyanobacterium cf. Symploca sp. Journal of Natural Products 76(11), 2026-2033 (2013).
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| 运输条件 | Room temperature in continental US; may vary elsewhere |
| 存放说明 | -20 |
| 纯度 | ≥95% |
| 计算分子量 | 278.4 |
| 分子式 | C15H22N2O3 |
| CAS号 | 1477949-42-0 |
| 稳定性 | ≥ 2 years |
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