Bohemine
货号：
21073-1mg 基本售价：
546.0 元 规格：
1 mg
产品信息
概述| 货号 | 21073-1mg |
| 描述 | Bohemine is a purine derivative that inhibits cyclin-dependent kinases (Cdks) (IC50s = 4.6, 8.3, and 2.7 µM for Cdk2/cyclin E, Cdk2/cyclin A, and Cdk9/cyclin T1, respectively).1 It has been shown to suppress cell growth and induce G1 and G2 phase cell cycle arrest in hybridoma cells.2 |
性能| 供应商 | Cayman |
| 应用文献 |
1.Raynaud, F.I.,Whittaker, S.R.,Fischer, P.M., et al. In vitro and in vivo pharmacokinetic-pharmacodynamic relationships for the trisubstituted aminopurine cyclin-dependent kinase inhibitors olomoucine, bohemine and CYC202. Clin. Cancer Res. 11(13), 4875-4887 (2005).
2.Francěk, F.,Strnad, M.,Havlíček, L., et al. Diverse effects of the cyclin-dependent kinase inhibitor bohemine: Concentration- and time-dependent suppression or stimulation of hybridoma culture. Cytotechnology 36(1-3), 117-123 (2001).
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| 运输条件 | Room temperature in continental US; may vary elsewhere |
| 存放说明 | -20 |
| 纯度 | ≥98% |
| 计算分子量 | 340.4 |
| 分子式 | C18H24N6O |
| CAS号 | 189232-42-6 |
| 稳定性 | ≥ 2 years |
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