BRD6688
货号：
19836-1mg 基本售价：
546.0 元 规格：
1 mg
产品信息
概述| 货号 | 19836-1mg |
| 描述 | BRD6688 is an HDAC inhibitor with IC50 values of 21 nM, 100 nM, and 11.48 µM for HDAC1, 2, and 3, respectively.1 It possesses preferential binding kinetics with six-fold extended half-life on HDAC2 compared to HDAC1 (381 min versus 65 min).1 BRD6688 crosses the blood brain barrier and has been shown to rescue the memory defects associated with p25 induced neurodegeneration in contextual fear conditioning in a CK-p25 mouse model of neurodegeneration.1 |
性能| 供应商 | Cayman |
| 应用文献 |
1.Wagner, F.F.,Zhang, Y.-L.,Fass, D.M., et al. Kinetically selective inhibitors of histone deacetylase 2 (HDAC2) as cognition enhancers. Chem.Sci. 6(1), 804-815 (2015).
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| 运输条件 | Room temperature in continental US; may vary elsewhere |
| 存放说明 | -20 |
| 纯度 | ≥98% |
| 计算分子量 | 282.3 |
| 分子式 | C16H18N4O |
| CAS号 | 1404562-17-9 |
| 稳定性 | ≥ 2 years |
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