CTPB
货号：
19570-1mg 基本售价：
546.0 元 规格：
1 mg
产品信息
概述| 货号 | 19570-1mg |
| 描述 | CTPB is an amide derivative that selectively activates the histone acetyltransferase (HAT) p300, with maximal activation at 275 µM.1 It directly binds p300.2 CTPB does not alter PCAF HAT or histone deacetylase activity.1 It dose-dependently increases the acetylation of histones H3 and H4, with maximal effect at 200 µM.1 |
性能| 供应商 | Cayman |
| 应用文献 |
1.Balasubramanyam, K.,Swaminathan, V.,Ranganathan, A., et al. Small molecule modulators of histone acetyltransferase p300. The Journal of Biological Chemisty 278(21), 19134-19140 (2003).
2.Devipriya, B.,Parameswari, A.R.,Rajalakshmi, G., et al. Exploring the binding affinities of p300 enzyme activators CTPB and CTB using docking method. Indian Journal of Biochemistry and Biophysics 47(6), 364-369 (2010).
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| 运输条件 | Room temperature in continental US; may vary elsewhere |
| 存放说明 | -20 |
| 纯度 | ≥98% |
| 计算分子量 | 554.1 |
| 分子式 | C31H43ClF3NO2 |
| CAS号 | 586976-24-1 |
| 稳定性 | ≥ 2 years |
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