| 货号 | 19459-1mg |
| 描述 | Zearalanone is a major phase I metabolite of the mycotoxin α-zearalanol (zeranol), a non-steroidal estrogen produced by fungi.1,2 Zearalanone is an estrogen receptor agonist (EC50 = 0.11 µM).3 It also acts as an androgen receptor antagonist.4 Zearalanone, zearalenone (Item No. 11353), and related compounds can be abundant in plant material infected with Fusarium.5 |
| 供应商 | Cayman |
| 应用文献 | |
| 1.Baldwin, R.S.,Williams, R.D. and Terry, M.K. Zeranol: A review of the metabolism, toxicology, and analytical methods for detection of tissue residues. Regul.Toxiocol.Pharmacol. 3(1), 9-25 (1983). 2.Migdalof, B.H.,Dugger, H.A.,Heider, J.G., et al. Biotransformation of zeranol: Disposition and metabolism in the female rat, rabbit, dog, monkey and man. Xenobiotica 13(4), 209-221 (1983). 3.Le Guevel, R. and Pakdel, F. Assessment of oestrogenic potency of chemicals used as growth promoter by in-vitro methods. Human Reproduction 16(5), 1030-1036 (2001). 4.Molina-Molina, J.M.,Real, M.,Jimenez-Diaz, I., et al. Assessment of estrogenic and anti-androgenic activities of the mycotoxin zearalenone and its metabolites using in vitro receptor-specific bioassays. Food and Chemical Toxicology 74, 233-239 (2016). 5.Aoyama, K.,Ishikuro, E.,Noriduki, H., et al. Formation ratios of zearalanone, zearalenols, and zearalanols versus zearalenone during incubation of Fusarium semitectum on sorghum and ratios in naturally contaminated sorghum. Food Hyg.Saf.Sci. 56(6), 247-251 (2015). | |
| 运输条件 | Room temperature in continental US; may vary elsewhere |
| 存放说明 | -20 |
| 纯度 | ≥98% |
| 计算分子量 | 320.4 |
| 分子式 | C18H24O5 |
| CAS号 | 5975-78-0 |
| 稳定性 | ≥ 2 years |
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