| 货号 | 18675-10g |
| 描述 | Phloxine B is a red dye, the USP grade of which is used as a color additive for food, drugs, and cosmetics.1 It has also been used as an alternative to Gram staining, to differentiate between Gram-negative and Gram-positive bacteria.2 At 100 µg/ml, it can inhibit methicillin-resistant S. aureusgrowthin vitro.3 Phloxine B has also been shown to modulate channel activity of wild-type cystic fibrosis transmembrane conductance regulator chloride channels (CFTR; Ki = 38 µM) and mutant delta F508 CFTR (Ki = 33 µM).4 |
| 别名 | Acid Red 92;Cyanosine;D&C Red No. 28; |
| 供应商 | Cayman |
| 应用文献 | |
| 1.Sabnis, R.W. Handbook of biological dyes and stains: Synthesis and industrial applications. (2010). 2.Rasooly, R. PhloxineB, aversatile bacterial stain. FEMS Immunology and Medical Microbiology 49(2), 261-265 (2007). 3.Rasooly, A. and Weisz, A. In vitro antibacterial activities of phloxine B and other halogenated fluoresceins against methicillin-resistant Staphylococcus aureus. Antimicrobial Agents and Chemotherapy 46(11), 3650-3653 (2002). 4.Melin, P.,Norez, C.,Callebaut, I., et al. The glycine residues G551 and G1349 within the ATP-binding cassette signature motifs play critical roles in the activation and inhibition of cystic fibrosis transmembrane conductance regulator channels by phloxine B. Journal of Membrane Biology 208(3), 203-212 (2005). | |
| 运输条件 | Room temperature in continental US; may vary elsewhere |
| 存放说明 | -20 |
| 纯度 | ≥95% |
| 计算分子量 | 829.6 |
| 分子式 | C20H2Br4Cl4O5 • 2Na |
| CAS号 | 18472-87-2 |
| 稳定性 | ≥ 2 years |
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