Estetrol
货号：
18232-500ug 基本售价：
546.0 元 规格：
500 ug
产品信息
概述| 货号 | 18232-500ug |
| 描述 | Estetrol is an estrogen steroid hormone exclusively produced by fetal liver from estradiol (Item No. 10006315) and estriol (Item No. 10006484) during pregnancy. It binds to estrogen receptors (ERs) with 4-fold higher affinity for ERα over ERβ and exhibits estrogenic effects in most tissues expressing ERs (bone, brain, vagina, and endometrium).1,2 In breast tumors, however, estetrol acts as an estrogen antagonist in the presence of estradiol, preventing tumor growth.1,2 |
| 别名 | E4;15α-Hydroxyestriol; |
性能| 供应商 | Cayman |
| 应用文献 |
1.Coelingh Bennink, H.J.T.,Holinka, C.F. and Diczfalusy, E. Estetrol review: Profile and potential clinical applications. Climacteric. 11(Suppl 1), 47-58 (2008).
2.Giretti, M.S.,Guevara, M.M.M.,Cecchi, E., et al. Effects of Estetrol on Migration and Invasion in T47-D Breast Cancer Cells through the Actin Cytoskeleton. Front.Endocrinol.(Lausanne) 5(80), 1-8 (2014).
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| 运输条件 | Room temperature in continental US; may vary elsewhere |
| 存放说明 | -20 |
| 纯度 | ≥95% |
| 计算分子量 | 304.4 |
| 分子式 | C18H24O4 |
| CAS号 | 15183-37-6 |
| 稳定性 | ≥ 2 years |
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