8-bromo-Cyclic AMP
货号:
18141-10mg 基本售价:
546.0 元 规格:
10 mg
产品信息
概述货号 | 18141-10mg |
描述 | 8-bromo-Cyclic AMP is a brominated derivative of cAMP that remains long-acting due to its resistance to degradation by cAMP phosphodiesterase.1,2 It can activate cAMP-dependent protein kinase, inhibiting growth, decreasing proliferation, increasing differentiation, and inducing apoptosis of cancer cells.2 |
别名 | 8-Bromoadenosine 3,5-cyclic monophosphate;8-bromo-cAMP;NSC 171719; |
性能供应商 | Cayman |
应用文献 |
1.Schwede, F.,Maronde, F.,Genieser, H., et al. Cyclic nucleotide analogs as biochemical tools and prospective drugs. Pharmacology & Therapeutics 87(2), 199-226 (2000). 2.Yokozaki, H.,Tortora, G.,Pepe, S., et al. Unhydrolyzable analogues of adenosine 3:5-monophosphate demonstrating growth inhibition and differentiation in human cancer cells. Cancer Research 52(9), 2504-2508 (1992).
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运输条件 | Room temperature in continental US; may vary elsewhere |
存放说明 | -20 |
纯度 | ≥95% |
计算分子量 | 408.1 |
分子式 | C10H11BrN5O6P |
CAS号 | 23583-48-4 |
稳定性 | ≥ 2 years |
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