5-PAHSA
货号：
17043-1mg 基本售价：
546.0 元 规格：
1 mg
产品信息
概述| 货号 | 17043-1mg |
| 描述 | Branched fatty acid esters of hydroxy fatty acids (FAHFAs) are newly identified endogenous lipids regulated by fasting and high-fat feeding and associated with insulin sensitivity.1 5-PAHSA is a FAHFA in which palmitic acid is esterified at the 5th carbon of hydroxy stearic acid. PAHSA isoforms are the most abundant forms of FAHFA identified in the adipose tissue of glucose tolerant AG4OX mice.1 PAHSAs are synthesized in vivo in both mice and humans and are regulated by fasting and high-fat feeding in mice.1 PAHSA levels correlate highly with insulin sensitivity and are reduced in adipose tissue and serum of insulin-resistant humans. PAHSA administration lowers ambient glycemia, improves glucose tolerance, and stimulates GLP-1 and insulin secretion in mice.1 |
性能| 供应商 | Cayman |
| 应用文献 |
1.Yore, M.M.,Syed, I.,Moraes-Vieira, P.M., et al. Discovery of a class of endogenous mammalian lipids with anti-diabetic and anti-inflammatory effects. Cell. 159(2), 318-332 (2014).
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| 运输条件 | Wet ice in continental US; may vary elsewhere |
| 存放说明 | -20 |
| 纯度 | ≥95% |
| 计算分子量 | 538.9 |
| 分子式 | C34H66O4 |
| CAS号 | 1481636-41-2 |
| 稳定性 | ≥ 1 year |
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