4-Thiouracil
货号：
16952-500mg 基本售价：
546.0 元 规格：
500 mg
产品信息
概述| 货号 | 16952-500mg |
| 描述 | 4-Thiouracil is a site-specific, photoactivatable probe used to detect RNA structures and nucleic acid-nucleic acid contacts.1 It absorbs ultraviolet light >300 nm and, in the presence of oxygen, acts as an energy donor to produce singlet oxygen by triplet-triplet energy transfer. The highly reactive oxygen species then reacts readily with 4-thiouracil, leading to the production of uracil and uracil-6-sulfonate, which is fluorescent at a wavelength of ~390 nm.2 4-Thiouracil is used as a T. gondii uracil phosphoribosyltransferase substrate to produce 4-thiouridine monophosphate, which can ultimately be incorporated into RNA.3 |
| 别名 | 2-hydroxy-4-Mercaptopyrimidine;NSC 43288;4-Thiopyrimidin-2-one;4-TU; |
性能| 供应商 | Cayman |
| 应用文献 |
1.Miller, M.R.,Robinson, K.J.,Cleary, M.D., et al. TU-tagging: Cell type-specific RNA isolation from intact complex tissues. Nature Methods 6(6), 439-441 (2009).
2.Zou, X.,Dai, X.,Liu, K., et al. Photophysical and photochemical properties of 4-thiouracil: Time-resolved IR spectroscopy and DFT studies. J.Phys.Chem.B. 118(22), 5864-5872 (2014).
3.Zeiner, G.M.,Cleary, M.D.,Fouts, A.E., et al. RNA analysis by biosynthetic tagging using 4-thiouracil and uracil phosphoribosyltransferase. Methods in Molecular Biology 418, 135-146 (2008).
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| 运输条件 | Room temperature in continental US; may vary elsewhere |
| 存放说明 | -20 |
| 纯度 | ≥98% |
| 计算分子量 | 128.1 |
| 分子式 | C4H4N2OS |
| CAS号 | 591-28-6 |
| 稳定性 | ≥ 2 years |
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