2-hexyl-4-Pentynoic Acid
货号：
15205-250mg 基本售价：
546.0 元 规格：
250 mg
产品信息
概述| 货号 | 15205-250mg |
| 描述 | 2-hexyl-4-Pentynoic acid is a derivative of valproic acid (Item No. 13033), an inhibitor of histone deacetylases (HDACs). It inhibits HDAC activity more potently (IC50 = 13 µM) than valproic acid (IC50 = 398 µM).1 2-hexyl-4-Pentynoic acid induces histone hyperacetylation in cerebellar granule cells significantly at 5 µM.1 It also induces the expression of heat shock proteins Hsp70-1a and Hsp70-1b and protects cerebellar granule cells from glutamate-induced excitotoxicity when used at a concentration of 50 µM.1 |
性能| 供应商 | Cayman |
| 应用文献 |
1.Leng, Y.,Marinova, Z.,Reis-Fernandes, M.A., et al. Potent neuroprotective effects of novel structural derivatives of valproic acid: Potential roles of HDAC inhibition and HSP70 induction. Neuroscience Letters 476(3), 127-132 (2010).
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| 运输条件 | Room temperature in continental US; may vary elsewhere |
| 存放说明 | -20 |
| 纯度 | ≥95% |
| 计算分子量 | 182.3 |
| 分子式 | C11H18O2 |
| CAS号 | 96017-59-3 |
| 稳定性 | ≥ 1 year |
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