Tosyllysine Chloromethyl Ketone (hydrochloride)
货号：
13074-50mg 基本售价：
546.0 元 规格：
50 mg
产品信息
概述| 货号 | 13074-50mg |
| 描述 | Tosyllysine chloromethylketone (TLCK) is an active site-directed agent that inhibits serine proteinases with trypsin-like activity. TLCK may also act non-selectively with thiol groups and thereby inhibit cysteine proteinases and other enzymes.1 To prevent proteolytic degradation, TLCK may be used in protein purification protocols.2 TLCK selectively inactiviates clostripain obtained from C. histolyticum.3 |
| 别名 | 1-Chloro-3-Toxylamide-7-Amino-L-2-Heptanone;TLCK; |
性能| 供应商 | Cayman |
| 应用文献 |
1.Griscavage, J.M.,Wilk, S. and Ignarro, L.J. Serine and cysteine proteinase inhibitors prevent nitric oxide production by activated macrophages by interfering with transcription of the inducible NO synthase gene. Biochemical and Biophysical Research Communications 215(2), 721-729 (1995).
2.Urban, M.K.,Franklin, S.G. and Zweidler, A. Isolation and characterization of the histone variants in chicken erythrocytes. Biochemistry 18(18), 3952-3960 (1979).
3.Józwiak, J.,Komar, A.,Jankowska, E., et al. Inhibition of Clostridium histolyticum supernatant cytotoxic activity by protease inhibitors. Enzyme and Microbial Technology 39, 28-31 (2006).
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| 运输条件 | Room temperature in continental US; may vary elsewhere |
| 存放说明 | -20 |
| 纯度 | ≥98% |
| 计算分子量 | 369.3 |
| 分子式 | C14H21ClN2O3S • HCl |
| CAS号 | 4272-74-6 |
| 稳定性 | ≥ 2 years |
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