| 货号 | 11858-100mg |
| 描述 | MNG-3 is an amphiphilic detergent for solubilization, stabilization, and crystallization of membrane proteins.1,2 It has a low critical micelle concentration (CMC = ~10 µM), which allows solubilization of membrane proteins without significantly inhibiting cell-free reactivity.1,3 MNG-3 has been used to recover diverse membrane proteins, including G protein-coupled receptors, respiratory complexes, transporters, photosynthetic protein complexes, and viral proteins.1,2,4,3 |
| 别名 | Lauryl Maltose Neopentyl Glycol;Maltose Neopentyl Glycol-3; |
| 供应商 | Cayman |
| 应用文献 | |
| 1.Chae, P.S.,Rasmussen, S.G.F.,Rana, R., et al. Maltose-neopentyl glycol (MNG) amphiphiles for solubilization, stabilization and crystallization of membrane proteins. Nat. Methods 7(12), 1003-1008 (2010). 2.Cho, K.H.,Husri, M.,Amin, A., et al. Maltose neopentyl glycol-3 (MNG-3) analogues for membrane protein study. Analyst 140(9), 3157-3163 (2015). 3.Fogeron, M.-L.,Badillo, A.,Jirasko, V., et al. Wheat germ cell-free expression: Two detergents with a low critical micelle concentration allow for production of soluble HCV membrane proteins. Protein Expr. Purif. 105, 39-46 (2015). 4.Chung, K.Y.,Kim, T.H.,Manglik, A., et al. Role of detergents in conformational exchange of a G protein-coupled receptor. J. Biol. Chem. 287(43), 36305-36311 (2012). | |
| 运输条件 | Wet ice in continental US; may vary elsewhere |
| 存放说明 | -20 |
| 纯度 | ≥95% |
| 计算分子量 | 1005.2 |
| 分子式 | C47H88O22 |
| CAS号 | 1257852-96-2 |
| 稳定性 | ≥ 2 years |
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