Dexamethasone
货号：
11015-500mg 基本售价：
546.0 元 规格：
500 mg
产品信息
概述| 货号 | 11015-500mg |
| 描述 | Dexamethasone is a synthetic glucocorticoid that binds the human glucocorticoid receptor with a higher affinity than a natural ligand, cortisol (Kd = 5 nM versus 17 nM, respectively).1 Through receptor activation, dexamethasone has both transactivating and transrepressing effects on gene expression, producing, in general, anti-inflammatory results.2 |
| 别名 | MK-125;NSC 34521; |
性能| 供应商 | Cayman |
| 应用文献 |
1.Mulatero, P.,Panarelli, M.,Schiavone, D., et al. Impaired cortisol binding to glucocorticoid receptors in hypertensive patients. Hypertension 30(5), 1274-1278 (1997).
2.Beck, I.M.,Vanden Berghe, W.,Vermeulen, L., et al. Crosstalk in inflammation: The interplay of glucocorticoid receptor-based mechanisms and kinases and phosphatases. Endocr. Rev. 30(7), 830-882 (2009).
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| 运输条件 | Room temperature in continental US; may vary elsewhere |
| 存放说明 | -20 |
| 纯度 | ≥98% |
| 计算分子量 | 392.5 |
| 分子式 | C22H29FO5 |
| CAS号 | 50-02-2 |
| 稳定性 | ≥ 2 years |
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