| 货号 | 20042-25mg |
| 描述 | Scopoletin is a natural coumarin found in a variety of plants, including some species from the genus Scopolia. Like esculetin (Item No. 19286), scopoletin binds iron and is used by plants to acquire iron from alkaline soil.1 Scopoletin inhibits aldose reductase activity in galactose-fed rats, upregulates PPARγ expression, and triggers phosphorylation of Nrf2 in animals.2,3,4 |
| 别名 | Esculetin 6-methyl ether;NSC 405647; |
| 供应商 | Cayman |
| 应用文献 | |
| 1.Clemens, S. and weber, M. The essential role of coumarin secretion for Fe acquisition from alkaline soil. Plant Signal.Behav. 11(2), (2016). 2.Chang, W.-C.,Wu, S.-C.,Xu, K.-D., et al. Scopoletin protects against methylglyoxal-induced hyperglycemia and insulin resistance mediated by suppression of advanced glycation endproducts (AGEs) generation and anti-glycation. Molecules 20(2), 2786-2801 (2015). 3.Kim, J.,Kim, C.-S.,Lee, Y.M., et al. Scopoletin inhibits rat aldose reductase activity and cataractogenesis in galactose-fed rats. Evid.Based Complement.Alternat.Med 2013:787138, (2013). 4.Zhang, W.Y.,Lee, J.-J.,Kim, Y., et al. Amelioration of insulin resistance by scopoletin in high-glucose-induced, insulin-resistant HepG2 cells. Horm.Metab.Res. 42(13), 930-935 (2010). | |
| 运输条件 | Wet ice in continental US; may vary elsewhere |
| 存放说明 | -20 |
| 纯度 | ≥98% |
| 计算分子量 | 192.2 |
| 分子式 | C10H8O4 |
| CAS号 | 92-61-5 |
| 稳定性 | ≥ 2 years |
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