货号 | 17629-5mg |
描述 | Fenoldopam is an agonist of dopamine D1A (D1R) and D1B (D5R) receptors (Kds = 17 and 11 nM, respectively).1,2 Fenoldopam is used to study the roles of these receptors, in cells and in vivo, and to alter hemodynamic properties, including hypertension, in animals.3,4 |
别名 | SKF 82526J; |
供应商 | Cayman |
应用文献 | |
1.Carey, R.M.,Stote, R.M.,Dubb, J.W., et al. Selective peripheral dopamine-1 receptor stimulation with fenoldopam in human essential hypertension. Journal of Clinical Investigation 74(6), 2198-2207 (1984). 2.Tiberi, M.,Jarvie, K.R.,Silvia, C., et al. Cloning, molecular characterization, and chromosomal assignment of a gene encoding a second D1 dopamine receptor subtype: Differential expression pattern in rat brain compared with the D1A receptor. Proceedings of the National Academy of Sciences of the United States of America 88, 7491-7495 (1991). 3.Gildea, J.J.,Shah, I.T.,Van Sciver, R., et al. The cooperative roles of the dopamine receptors, D1R and D5R, on the regulation of renal sodium transport. Kidney International 86(1), 118-126 (2014). 4.Swanson, T.A.,Conte, T.,Deeley, B., et al. Hemodynamic correlates of drug-induced vascular injury in the rat using high-frequency ultrasound imaging. Toxicologic Pathology 42(4), 784-791 (2014). | |
运输条件 | Room temperature in continental US; may vary elsewhere |
存放说明 | -20 |
纯度 | ≥95% |
计算分子量 | 401.9 |
分子式 | C16H16ClNO3 • CH3SO3H |
CAS号 | 67227-57-0 |
稳定性 | ≥ 2 years |
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