MNS
货号：
15206-10mg 基本售价：
532.0 元 规格：
10 mg
产品信息
概述| 货号 | 15206-10mg |
| 描述 | MNS is a β-nitrostyrene that blocks and reverses platelet aggregation induced by such triggers as collagen, U-46619 (Item No. 16450), and ADP (IC50 = 1.1, 2.1, and 4.1 µM, respectively).1,2 It reduces tyrosine phosphorylation in stimulated platelets and inhibits recombinant human Syk and Src (IC50 = 2.8 and 27.3 µM, respectively) in vitro.1,3 |
| 别名 | 3,4-Methylenedioxy-β-nitrostyrene;NSC 10120;NSC 105303;NSC 170724;Syk Inhibitor III; |
性能| 供应商 | Cayman |
| 应用文献 |
1.Wang, W.Y.,Wu, Y.C. and Wu, C.C. Prevention of platelet glycoprotein IIb/IIIa activation by 3,4-methylenedioxy-β-nitrostyrene, a novel tyrosine kinase inhibitor. Molecular Pharmacology 70(4), 1380-1389 (2006).
2.Hsieh, P.W.,Chang, Y.T.,Chuang, W.Y., et al. The synthesis and biologic evaluation of anti-platelet and cytotoxic β-nitrostyrenes. Bioorganic & Medicinal Chemistry 18(21), 7621-7627 (2010).
3.Wang, W.Y.,Hsieh, P.W.,Wu, Y.C., et al. Synthesis and pharmacological evaluation of novel β-nitrostyrene derivatives as tyrosine kinase inhibitors with potent antiplatelet activity. Biochemical Pharmacology 74(4), 601-611 (2007).
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| 运输条件 | Room temperature in continental US; may vary elsewhere |
| 存放说明 | -20 |
| 纯度 | ≥95% |
| 计算分子量 | 193.2 |
| 分子式 | C9H7NO4 |
| CAS号 | 1485-00-3 |
| 稳定性 | ≥ 2 years |
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