AEBSF (hydrochloride)
货号：
14321-50mg 基本售价：
532.0 元 规格：
50 mg
产品信息
概述| 货号 | 14321-50mg |
| 描述 | AEBSF is a water soluble, irreversible, broad spectrum inhibitor of serine proteases, including trypsin, chymotrypsin, plasmin, thrombin, and kallikreins.1 AEBSF can also prevent the activation of the ROS generator, NADPH oxidase.2 At 10-50 μg, AEBSF can attenuate airway inflammation in a mouse model of airway allergy.3 AEBSF maintains stability in slightly acidic aqueous solutions and serves as a nontoxic alternative to the organophosphate inhibitors, PMSF and DFP.1 |
| 别名 | Pefabloc SC; |
性能| 供应商 | Cayman |
| 应用文献 |
1.Powers, J.C.,Asgian, J.L.,Ekici, Ö.D., et al. Irreversible inhibitors of serine, cysteine, and threonine proteases. Chemical Reviews 102, 4639-4750 (2002).
2.Diatchuk, V.,Lotan, O.,Koshkin, V., et al. Inhibition of NADPH oxidase activation by 4-(2-aminoethyl)-benzenesulfonyl fluoride and related compounds. The Journal of Biological Chemisty 272(20), 13292-13301 (1997).
3.Saw, S.,Kale, S.L. and Arora, N. Serine protease inhibitor attenuates ovalbumin induced inflammation in mouse model of allergic airway disease. PLoS One 7(7), (2012).
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| 运输条件 | Room temperature in continental US; may vary elsewhere |
| 存放说明 | -20 |
| 纯度 | ≥98% |
| 计算分子量 | 239.7 |
| 分子式 | C8H10FNO2S • HCl |
| CAS号 | 30827-99-7 |
| 稳定性 | ≥ 2 years |
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