Neomycin (sulfate)
货号：
14287-100g 基本售价：
532.0 元 规格：
100 g
产品信息
概述| 货号 | 14287-100g |
| 描述 | Neomycin is an aminoglycoside antibiotic produced by S. fradiae that inhibits protein translation by binding to the small subunit of prokaryotic ribosomes.1 It blocks voltage-sensitive Ca2+ channels and is a potent inhibitor of skeletal muscle sarcoplasmic reticulum Ca2+release.2 Neomycin has been shown to inhibit inositol phospholipid turnover, phospholipase C, and phosphatidylcholine-phospholipase D activity (IC50 = 65 µM).3 It is highly effective against Gram-positive and Gram-negative bacteria and is commonly used for the prevention of bacterial contamination of cell cultures. |
性能| 供应商 | Cayman |
| 应用文献 |
1.Wilson, D.N. The A-Z of bacterial translation inhibitors. Crit. Rev. Biochem. Mol. Biol. 44(6), 393-433 (2009).
2.Vergara, J.,Tsien, R.Y. and Delay, M. Inositol 1,4,5-trisphosphate: A possible chemical link in excitation-contraction coupling in muscle. Proceedings of the National Academy of Sciences of the United States of America 82(18), 6352-6356 (1985).
3.Liscovitch, M.,Chalifa, V.,Danin, M., et al. Inhibition of neural phospholipase D activity by aminoglycoside antibiotics. Biochemistry Journal 279, 319-321 (1991).
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| 运输条件 | Room temperature in continental US; may vary elsewhere |
| 存放说明 | 22 |
| 纯度 | ≥90% |
| 计算分子量 | 908.9 |
| 分子式 | C23H46N6O13 • 3H2SO4 |
| CAS号 | 1405-10-3 |
| 稳定性 | ≥ 2 years |
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