Capecitabine
货号：
10487-500mg 基本售价：
532.0 元 规格：
500 mg
产品信息
概述| 货号 | 10487-500mg |
| 描述 | 5-Fluorouracil (5-FU) is a pyrimidine analog which noncompetitively inhibits thymidylate synthase, interfering with DNA synthesis. It has been used for the treatment of cancer for several decades. Capecitabine is a fluoropyrimidine carbamate which acts as a prodrug, being enzymatically converted to 5-FU by enzymes concentrated in the liver and in cancer tissue.1 The selective localization of these processing enzymes, and in particular, thymidine phosphorylase in tumor tissues, targets the production of the active product, 5-FU, in cancer cells.1 |
| 别名 | Ro 09-1978;Xeloda®; |
性能| 供应商 | Cayman |
| 应用文献 |
1.Miwa, M.,Ura, M.,Nishida, M., et al. Design of a novel oral fluoropyrimidine carbamate, capecitabine, which generates 5-fluorouracil selectively in tumours by enzymes concentrated in human liver and cancer tissue. European Journal of Cancer 34(8), 1274-1281 (1998).
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| 运输条件 | Room temperature in continental US; may vary elsewhere |
| 存放说明 | -20 |
| 纯度 | ≥98% |
| 计算分子量 | 359.4 |
| 分子式 | C15H22FN3O6 |
| CAS号 | 154361-50-9 |
| 稳定性 | ≥ 2 years |
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