| 货号 | 10008643-25ug |
| 描述 | Prostaglandin F2α-d9(PGF2α-d9) contains nine deuterium atoms at the 17, 17, 18, 18, 19, 19, 20, 20, and 20 positions. It is intended for use as an internal standard for the quantification of PGF2α by GC- or LC-mass spectrometry. PGF2α is a widely distributed PG occurring in many species.1,2,3 It causes contraction of vascular, bronchial, intestinal, and myometrial smooth muscle, and also exhibits potent luteolytic activity.1PGF2α exerts its receptor mediated physiological activity at 50-100 nM.1 Maximal ovine myometrial contraction can be achieved at 125 nM PGF2αin vitro.4 |
| 别名 | Dinoprost-d9; |
| 供应商 | Cayman |
| 应用文献 | |
| 1.Samuelsson, B.,Goldyne, M.,Granström, E., et al. Prostaglandins and thromboxanes. Annual Reviews of Biochemistry 47, 997-1029 (1978). 2.Speroff, L., and Ramwell, P.W. Prostaglandins in reproductive physiology. American Journal of Obstetics and Gynecology 107, 1111-1130 (1970). 3.Watanabe, K.,Iguchi, Y.,Iguchi, S., et al. Stereospecific conversion of prostaglandin D2 to (5Z,13E)-(15S)-9α,-11β,15-trihydroxyprosta-5,13-dien-1-oic acid (9α,11β-prostaglandin F2) and of prostaglandin H2 to prostaglandin F2α by bovine lung prostaglandin F synthase. Proceedings of the National Academy of Sciences of the United States of America 83, 1583-1587 (1986). 4.Crankshaw, D.J., and Gaspar, V. Pharmacological characterization in vitro of prostanoid receptors in the myometrium of nonpregnant ewes. Journal of Reproduction and Fertility 103, 55-61 (1995). | |
| 运输条件 | Wet ice in continental US; may vary elsewhere |
| 存放说明 | -20 |
| 纯度 | ≥99% deuterated forms (d1-d9) |
| 计算分子量 | 363.5 |
| 分子式 | C20H25D9O5 |
| 稳定性 | ≥ 1 year |
| 本官网所有报价均为常温或者蓝冰运输价格，如有产品需要干冰运输，需另外加收干冰运输费。 |