| 货号 | 17327-1mg |
| 描述 | Coenzyme Q10 (Item No. 11506) is a component of the electron transport chain and participates in aerobic cellular respiration, generating energy in the form of ATP.1 In its reduced form, it acts as an antioxidant.1 Coenzyme Q2 is a precursor of coenzyme Q10 that has 2, rather than 10, isoprenoid units on the ubiquinone base. It can act as an electron acceptor for bacterial Complex I.2 In mammalian cells, exogenous coenzyme Q2 prevents the production of reactive oxygen species associated with Complex I activity.3,4 Forms of coenzyme Q with shorter isoprenoid chains, including coenzyme Q2, induce p53-dependent apoptosis in human B-cell acute lymphoblastoid leukemia BALL-1 cells.5 |
| 别名 | CoQ2;Ubiquinone-2;Ubiquinone Q2; |
| 供应商 | Cayman |
| 应用文献 | |
| 1.Crane, F.L. Biochemical functions of coenzyme Q10. Journal of the American College of Nutrition 20(6), 591-598 (2001). 2.David, P.,Baumann, M.,Wikström, M., et al. Interaction of purified NDH-1 from Escherichia coli with ubiquinone analogues. Biochimica et Biophysica Acta 1553(3), 268-278 (2002). 3.Fato, R.,Estornell, E.,DiBernardo, S., et al. Steady-state kinetics of the reduction of coenzyme Q analogs by complex I (NADH:ubiquinone oxidoreductase) in bovine heart mitochondria and submitochondrial particles. Biochem. 35(8), 2705-2716 (1996). 4.Fato, R.,Bergamini, C.,Bortolus, M., et al. Differential effects of mitochondrial Complex I inhibitors on production of reactive oxygen species. Biochim.Biophys.Acta. 1787(5), 384-392 (2009). 5.Esaka, Y.,Nagahara, Y.,Hasome, Y., et al. Coenzyme Q2 induced p53-dependent apoptosis. Biochim.Biophys.Acta. 1724(1-2), 49-58 (2005). | |
| 运输条件 | Room temperature in continental US; may vary elsewhere |
| 存放说明 | -20 |
| 纯度 | ≥98% |
| 计算分子量 | 318.4 |
| 分子式 | C19H26O4 |
| CAS号 | 606-06-4 |
| 稳定性 | ≥ 2 years |
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