货号 | 50211-25ug |
描述 | (±)5(6)-EET is biosynthesized in rat and rabbit liver microsomes by CYP450.1,2 In neuroendocrine cells, such as the anterior pituitary and pancreatic islet, (±)5(6)-EET has been implicated in the mobilization of Ca2+ and hormone secretion.3,4 |
别名 | (±)5,6-EpETrE; |
供应商 | Cayman |
应用文献 | |
1.Chacos, N.,Falck, J.R.,Wixtrom, C., et al. Novel epoxides formed during the liver cytochrome P-450 oxidation of arachidonic acid. Biochemical and Biophysical Research Communications 104, 916-922 (1982). 2.Oliw, E.H.,Guengerich, F.P. and Oates, J.A. Oxygenation of arachidonic acid by hepatic monooxygenases. Isolation and metabolism of four epoxide intermediates. The Journal of Biological Chemisty 257, 3771-3781 (1982). 3.Snyder, C.,Lattanzio, F.,Yadagiri, P., et al. 5,6-Epoxyeicosatrienoic acid mobilizes Ca2+ in anterior pituitary cells. Biochemical and Biophysical Research Communications 139, 1188-1194 (1986). 4.Falck, J.R.,Manna, S.,Moltz, J., et al. Epoxyeicosatrienoic acids stimulate glucagon and insulin release from isolated rat pancreatic islets. Biochemical and Biophysical Research Communications 114, 743-749 (1983). | |
运输条件 | Dry ice in continental US; may vary elsewhere |
存放说明 | -80 |
纯度 | ≥98% |
计算分子量 | 320.5 |
分子式 | C20H32O3 |
CAS号 | 87173-80-6 |
稳定性 | ≥ 6 months |
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