Cantharidin
货号：
14589-25mg 基本售价：
504.0 元 规格：
25 mg
产品信息
概述| 货号 | 14589-25mg |
| 描述 | Cantharidin is a natural toxin produced by blister beetles that moderately inhibits protein phosphatases 1 (PP1) (IC50 = 1.7 μM) and PP2A (IC50 = 0.2 μM) and only weakly inhibits the activity of PP2B (IC50 = 1 mM).1,2 It has been shown to stimulate cell cycle progression and induce premature mitosis, used topically (0.7%) as an anti-wart treatment, and has been shown to be active in cervical, tongue, neuroblastoma, bone, leukemia, ovarian, colon, and various other cancer cell lines.2 |
| 别名 | NSC 61805; |
| 是否危险品 | 是 |
性能| 供应商 | Cayman |
| 应用文献 |
1.Honkanen, R.E. Cantharidin, another natural toxin that inhibits the activity of serine/threonine protein phosphatases types 1 and 2A. FEBS Letters 330(3), 283-286 (1993).
2.McCluskey, A.,Sim, A.T.R. and Sakoff, J.A. Serine-threonine protein phosphatase inhibitors: Development of potential therapeutic strategies. Journal of Medicinal Chemistry 45(6), 1151-1175 (2002).
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| 运输条件 | Room temperature in continental US; may vary elsewhere |
| 存放说明 | 4 |
| 纯度 | ≥98% |
| 计算分子量 | 196.2 |
| 分子式 | C10H12O4 |
| CAS号 | 56-25-7 |
| 稳定性 | ≥ 6 months |
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