FKGK 11
货号：
13179-500ug 基本售价：
504.0 元 规格：
500 ug
产品信息
概述| 货号 | 13179-500ug |
| 描述 | Phospholipase A2(PLA2) catalyzes the hydrolysis of fatty acids at the sn-2 position of glycerophospholipids, yielding a free fatty acid and a lysophospholipid as products. There are three broad classes of PLA2, secretory (sPLA2), calcium-dependent cytosolic (cPLA2), and calcium-independent cytosolic (iPLA2), that have different functions. FKGK 11 is a selective inhibitor of iPLA2 that demonstrates an XI(50) value of 0.0073, where XI(50) equals the mole fraction of FKGK 11 in the total substrate interface required to inhibit iPLA2 by 50%.1 In comparison, mole fractions as high as 0.091 do not inhibit cPLA2 activity and cause only slight inhibition of sPLA2.1 |
性能| 供应商 | Cayman |
| 应用文献 |
1.Baskakis, C.,Magrioti, V.,Cotton, N., et al. Synthesis of polyfluoro ketones for selective inhibition of human phospholipase A2 enzymes. Journal of Medicinal Chemistry 51, 8027-8037 (2008).
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| 运输条件 | Room temperature in continental US; may vary elsewhere |
| 存放说明 | -20 |
| 纯度 | ≥98% |
| 计算分子量 | 280.2 |
| 分子式 | C13H13F5O |
| CAS号 | 1071000-98-0 |
| 稳定性 | ≥ 2 years |
声明| 本官网所有报价均为常温或者蓝冰运输价格，如有产品需要干冰运输，需另外加收干冰运输费。 |
