| 货号 | 11726-100mg |
| 描述 | Oleanolic acid is a triterpenoid that is synthesized in many plants by the cyclization of squalene. Traditionally used in Asian medicine, oleanolic acid has long been known to have anti-inflammatory, anti-hyperlipidemic, and hepatoprotective in vivoeffects.1,2,3 It has also been found to have antiviral and anti-tumor actions.4,2 Synthetic triterpenoids based on oleanolic acid have been shown to bind specific proteins by Michael addition.5 Important protein targets include Keap1, IKK, JAK1, STAT3, PTEN, and proteins associated with the actin cytoskeleton.5 |
| 别名 | Astrantiagenin C;Caryophyllin;Giganteumgenin C;Gledigenin 1;NSC 114945;Oleanoic Acid;Virgaureagenin B; |
| 供应商 | Cayman |
| 应用文献 | |
| 1.Liu, J. Pharmacology of oleanolic acid and ursolic acid. Journal of Ethnopharmacology 49, 57-68 (1995). 2.Liby, K.T.,Yore, M.M., and Sporn, M.B. Triterpenoids and rexinoids as multifunctional agents for the prevention and treatment of cancer. Cancer 7, 357-369 (2007). 3.Sultana, N., and Ata, A. Oleanolic acid and related derivatives as medicinally important compounds. Journal of Enzyme Inhibition and Medicinal Chemistry 23(6), 739-756 (2008). 4.Kashiwada, Y.,Wang, H.K.,Nagao, T., et al. Anti-AIDS agents. 30. Anti-HIV activity of oleanolic acid, pomolic acid, and structurally related triterpenoids. J.Nat.Prod 61, 1090-1095 (1998). 5.Sporn, M.B.,Liby, K.T.,Yore, M.M., et al. New synthetic triterpenoids: potent agents for prevention and treatment of tissue injury caused by inflammatory and oxidative stress. Journal of Natural Products 74, 537-545 (2011). | |
| 运输条件 | Room temperature in continental US; may vary elsewhere |
| 存放说明 | -20 |
| 纯度 | ≥95% |
| 计算分子量 | 456.7 |
| 分子式 | C30H48O3 |
| CAS号 | 508-02-1 |
| 稳定性 | ≥ 2 years |
| 本官网所有报价均为常温或者蓝冰运输价格，如有产品需要干冰运输，需另外加收干冰运输费。 |