Prostaglandin A2-d4
货号：
310210-50ug 基本售价：
490.0 元 规格：
50 ug
产品信息
概述| 货号 | 310210-50ug |
| 描述 | Prostaglandin A2-d4(PGA2-d4) contains four deuterium atoms at the 3, 3, 4, and 4 positions. It is intended for use as an internal standard for the quantification of PGA2 by GC- or LC- mass spectrometry. PGA2 is a naturally occurring prostaglandin in gorgonian corals where it may function in self defense. It is generally not present in mammals. It has low biological potency in most bioassays, but does show some antiviral/antitumor activity.1 At a 25 µM concentration, PGA2 blocks the cell cycle progression of NIH 3T3 cells at the G1 and G2/M phase.2 It has also been shown to act as a vasodilator with natriuretic properties.3 |
| 别名 | PGA2-d4;Medullin-d4; |
性能| 供应商 | Cayman |
| 应用文献 |
1.Fukushima, M.,Kato, T.,Narumiya, S., et al. Prostaglandin A and J: Antitumor and antiviral prostaglandins. Advances in Prostaglandin, Thromboxane, and Leukotriene Research 19, 415-418 (1989).
2.Hitomi, M.,Shu, J.,Strom, D., et al. Prostaglandin A2 blocks the activation of G1 phase cyclin-dependent kinase without altering mitogen-activated protein kinase stimulation. The Journal of Biological Chemisty 271, 9376-9383 (1996).
3.Frolich, J.C.,Sweetman, B.J.,Carr, K., et al. Assessment of the levels of PGA2 in human plasma by gas chromatography-mass spectrometry. Prostaglandins 10, 185-195 (1975).
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| 运输条件 | Wet ice in continental US; may vary elsewhere |
| 存放说明 | -20 |
| 纯度 | ≥99% deuterated forms (d1-d4) |
| 计算分子量 | 338.5 |
| 分子式 | C20H26D4O4 |
| CAS号 | 201608-18-6 |
| 稳定性 | ≥ 1 year |
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