N-Methylnicotinamide
货号：
21850-5g 基本售价：
490.0 元 规格：
5 g
产品信息
概述| 货号 | 21850-5g |
| 描述 | N’-Methylnicotinamide is a metabolite of nicotinamide (Item No. 11127) produced by the action of nicotinamide N-methyltransferase (NNMT). It has multiple effects on endothelial cells: it inhibits thrombus formation, increases skin vascular permeability, and prevents atherosclerosis in rodent models.1,2,3 |
| 别名 | Nicotinic Acid Methylamide;NSC 66521;SR 4415; |
性能| 供应商 | Cayman |
| 应用文献 |
1.Mogielnicki, A.,Kramkowski, K.,Pietrzak, L., et al. N-methylnicotinamide inhibits arterial thrombosis in hypertensive rats. J. Physiol. Pharmacol. 58(3), 515-527 (2007).
2.Pietrzak, L.,Mogielnicki, A., and Buczko, W. Nicotinamide and its metabolite N-methylnicotinamide increase skin vascular permeability in rats. Clin. Exp. Dermatol. 34(3), 380-384 (2009).
3.Jiang, N.,Wang, M.,Song, J., et al. N-methylnicotinamide protects against endothelial dysfunction and attenuates atherogenesis in apolipoprotein E-deficient mice. Mol. Nutr. Food Res. 60(7), 1625-1636 (2016).
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| 运输条件 | Room temperature in continental US; may vary elsewhere |
| 存放说明 | -20 |
| 纯度 | ≥98% |
| 计算分子量 | 136.2 |
| 分子式 | C7H8N2O |
| CAS号 | 114-33-0 |
| 稳定性 | ≥ 2 years |
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