| 货号 | 21595-25mg |
| 描述 | Zeocin is a natural copper-chelated glycopeptide antibiotic that is structurally and functionally related to bleomycin (Item No. 13877).1 Like bleomycin, zeocin intercalates into DNA and induces DNA breaks. Zeocin is cytotoxic against bacterial, fungal, plant, and animal cells. Resistance to zeocin is conferred by the binding protein coded by the bleomycin-resistance gene (ble) from a tallysomycin-producing strain of S. hindustanus(Sh).1,2 The resistance gene Sh ble is used as a selectable marker in conjunction with zeocin in molecular biology.3,4 |
| 别名 | Phleomycin D1;PLM D1; |
| 供应商 | Cayman |
| 应用文献 | |
| 1.Hecht, S.M. Bleomycin: New perspectives on the mechanism of action. J. Nat. Prod. 63, 158-168 (2000). 2.Gatignol, A.,Durand, H., and Tiraby, G. Bleomycin resistance conferred by a drug-binding protein. FEBES Lett. 230(1-2), 171-175 (1988). 3.Choi, K.-H.,Mima, T.,Casart, Y., et al. Genetic tools for select-agent-compliant manipulation of Burkholderia pseudomallei. Appl. Environ. Microbiol. 74(4), 1064-1075 (2008). 4.Lin-Cereghino, J.,Hashimoto, M.D.,Moy, A., et al. Direct selection of Pichia pastoris expression strains using new G418 resistance vectors. Yeast 25(4), 293-299 (2008). | |
| 运输条件 | Room temperature in continental US; may vary elsewhere |
| 存放说明 | -20 |
| 纯度 | ≥95% |
| 计算分子量 | 1427.5 |
| 分子式 | C55H86N20O21S2 |
| CAS号 | 11031-11-1 |
| 稳定性 | ≥ 2 years |
| 本官网所有报价均为常温或者蓝冰运输价格，如有产品需要干冰运输，需另外加收干冰运输费。 |