| 货号 | 20573-1mg |
| 描述 | CP21R7 is a potent and selective inhibitor of GSK3β.1 It is used as an activator of stem cells prior to the induction of differentiation of stem cells to endothelial and smooth muscle cells.2,3,4 GSK3β inhibitors, including CP21R7, can be used with BMP4 to commit human pluripotent stem cells to a mesodermal fate.3,4 |
| 供应商 | Cayman |
| 应用文献 | |
| 1.Gong, L.,Hirschfeld, D.,Tan, Y.-C., et al. Discovery of potent and bioavailable GSK-3β inhibitors. Bioorg. Med. Chem. Lett. 20(5), 1693-1696 (2010). 2.Christensen, K.,Graf, M.,Iacone, R., et al. Method for differentiation of pluripotent stem cells into vascular bed cells. (2015). 3.Patsch, C.,Challet-Meylan, L.,Thoma, E.C., et al. Generation of vascular endothelial and smooth muscle cells from human pluripotent stem cells. Nat. Cell Biol. 17(8), 994-1003 (2015). 4.Sahara, M.,Hansson, E.M.,Wernet, O., et al. Manipulation of a VEGF-Notch signaling circuit drives formation of functional vascular endothelial progenitors from human pluripotent stem cells. Cell Res. 24(7), 820-841 (2014). | |
| 运输条件 | Wet ice in continental US; may vary elsewhere |
| 存放说明 | -20 |
| 纯度 | ≥98% |
| 计算分子量 | 317.3 |
| 分子式 | C19H15N3O2 |
| CAS号 | 125314-13-8 |
| 稳定性 | ≥ 2 years |
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