JNJ-42165279
货号：
19987-1mg 基本售价：
490.0 元 规格：
1 mg
产品信息
概述| 货号 | 19987-1mg |
| 描述 | JNJ-42165279 is a potent, irreversible inhibitor of fatty acid amide hydrolase (FAAH; IC50s = 70 and 313 nM for human and rat forms, respectively).1 It displays selectivity for FAAH over a panel of other enzymes, receptors, transporters, and ion channels. JNJ-42165279 is active in vivo, blocking FAAH activity in brain and periphery of rats and raising concentrations of anandamide (Item No. 90050), oleoyl ethanolamide (Item No. 90265), and palmitoyl ethanolamide (Item No. 90350).1 It is also efficacious in the spinal nerve ligation model of neuropathic pain.1 |
性能| 供应商 | Cayman |
| 应用文献 |
1.Keith, J.M.,Jones, W.M.,Tichenor, M., et al. Preclinical characterization of the FAAH inhibitor JNJ-42165279. ACS Med.Chem.Lett 6(12), 1204-1208 (2015).
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| 运输条件 | Wet ice in continental US; may vary elsewhere |
| 存放说明 | -20 |
| 纯度 | ≥98% |
| 计算分子量 | 410.8 |
| 分子式 | C18H17ClF2N4O3 |
| CAS号 | 1346528-50-4 |
| 稳定性 | ≥ 2 years |
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