Ripasudil (hydrochloride hydrate)
货号：
19920-1mg 基本售价：
490.0 元 规格：
1 mg
产品信息
概述| 货号 | 19920-1mg |
| 描述 | Ripasudil is an inhibitor of Rho-associated protein kinase (ROCK; IC50s = 51 and 19 nM for ROCK-I and ROCK-II, respectively).1 Formulations containing ripasudil are used to lower intraocular pressure in the context of glaucoma and ocular hypertension.1,2,3 |
| 别名 | K-115; |
性能| 供应商 | Cayman |
| 应用文献 |
1.Isobe, T.,Mizuno, K.,Kaneko, Y., et al. Effects of K-115, a rho-kinase inhibitor, on aqueous humor dynamics in rabbits. Curr. Eye Res. 39(8), 813-822 (2014).
2.Kaneko, Y.,Ohta, M.,Inoue, T., et al. Effects of K-115 (Ripasudil), a novel ROCK inhibitor, on trabecular meshwork and Schlemm’s canal endothelial cells. Sci. Rep. 6, 19640 (2016).
3.Sato, S.,Hirooka, K.,Nitta, E., et al. Additive intraocular pressure lowering effects of the Rho kinase inhibitor, ripasudil in glaucoma patients not able to obtain adequate control after other maximal tolerated medical therapy. Adv. Ther. 33(9), 1628-1634 (2016).
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| 运输条件 | Wet ice in continental US; may vary elsewhere |
| 存放说明 | -20 |
| 纯度 | ≥98% |
| 计算分子量 | 395.9 |
| 分子式 | C15H18FN3O2S • HCl [2H2O] |
| CAS号 | 887375-67-9 |
| 稳定性 | ≥ 2 years |
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