Schisandrin A
货号：
19849-5mg 基本售价：
490.0 元 规格：
5 mg
产品信息
概述| 货号 | 19849-5mg |
| 描述 | Schisandrin A is a lignan found in the fruits of several species of the Schisandra genus that is reported to have liver-protective, antitumor, and antioxidant activities in various research models. It has been identified as an agonist of the adiponectin receptor 2 with an IC50 value of 3.5 µM.1 Schisandrin A has also been shown to have a protective role in a rat model of myocardial ischemia-reperfusion injury.2 Furthermore, schisandrin A can down-regulate the increased production of nitric oxide, TNF-α and IL-6 induced by lipopolysaccharide both in BV-2 cells and primary microglia cells.3 |
| 别名 | Deoxyschizandrin;Wuweizisu A; |
性能| 供应商 | Cayman |
| 应用文献 |
1.Sun, Y.,Zang, Z.,Zhong, L., et al. Identification of adiponectin receptor agonist utilizing a fluorescence polarization based high throughput assay. PLoS One 8(5), (2013).
2.Chang, R.,Li, Y.,Yang, X., et al. Protective role of deoxyschizandrin and schisantherin A against myocardial ischemia-reperfusion injury in rats. PloS One 8(4), (2013).
3.Song, F.,Zeng, K.,Liao, L., et al. Schizandrin A inhibits microglia-mediated neuroninflammation through inhibiting TRAF6-NF-κB and Jak2-stat3 signaling pathways. PloS One 11(2), (2016).
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| 运输条件 | Room temperature in continental US; may vary elsewhere |
| 存放说明 | -20 |
| 纯度 | ≥98% |
| 计算分子量 | 416.5 |
| 分子式 | C24H32O6 |
| CAS号 | 61281-38-7 |
| 稳定性 | ≥ 2 years |
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