Dirithromycin
货号：
19466-250mg 基本售价：
490.0 元 规格：
250 mg
产品信息
概述| 货号 | 19466-250mg |
| 描述 | Dirithromycin is a macrolide antibiotic. It is a prodrug of erythromycylamine that has outstanding activity against Campylobacter.1 Dirithromycin is a group 3 agent with respect to its interaction with the cytochrome P450 (CYP) isoform 3A4, as it interferes poorly with CYP3A4 in vitro and generally does not alter drug metabolism in vivo.2 |
| 别名 | Antibiotic AS-E 136;LY237216; |
性能| 供应商 | Cayman |
| 应用文献 |
1.Hardy, D.J.,Hensey, D.M.,Beyer, J.M., et al. Comparative in vitro activities of new 14-, 15-, and 16-membered macrolides. Antimicrobial Agents and Chemotherapy 32(11), 1710-1719 (1988).
2.Westphal, J.F. Macrolide - induced clinically relevant drug interactions with cytochrome P-450A (CYP) 3A4: An update focused on clarithromycin, azithromycin and dirithromycin. British Journal of Clinical Pharmacology 50(4), 285-295 (2000).
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| 运输条件 | Room temperature in continental US; may vary elsewhere |
| 存放说明 | -20 |
| 纯度 | ≥95% |
| 计算分子量 | 835.1 |
| 分子式 | C42H78N2O14 |
| CAS号 | 62013-04-1 |
| 稳定性 | ≥ 2 years |
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