LY2409881
货号：
18774-1mg 基本售价：
490.0 元 规格：
1 mg
产品信息
概述| 货号 | 18774-1mg |
| 描述 | LY2409881 is a selective inhibitor of IκB kinase β (IKK2; IC50 = 30 nM).1 It inhibits IKK1 and other common kinases at ≥10-fold higher concentrations.1 LY2409881 has been shown to suppress constitutively activated NF-κB and to induce apoptosis in lymphoma cells both in vitro and in preclinical mouse models of B and T cell lymphoma both as a single agent and in combination with histone deacetylase inhibitors.1 |
性能| 供应商 | Cayman |
| 应用文献 |
1.Deng, C.,Lipstein, M.,Rodriguez, R., et al. The novel IKK2 inhibitor LY2409881 potently synergizes with histone deacetylase inhibitors in preclinical models of lymphoma through the downregulation of NF-κB. Clin. Cancer. Res 21(1), 134-145 (2015).
|
| 运输条件 | Room temperature in continental US; may vary elsewhere |
| 存放说明 | -20 |
| 纯度 | ≥98% |
| 计算分子量 | 594.4 |
| 分子式 | C24H29ClN6OS • 3HCl |
| CAS号 | 946518-60-1 |
| 稳定性 | ≥ 2 years |
声明| 本官网所有报价均为常温或者蓝冰运输价格，如有产品需要干冰运输，需另外加收干冰运输费。 |
