| 货号 | 18741-1mg |
| 描述 | Cooenzyme Q10(CoQ10) is a component of the electron transport chain and participates in aerobic cellular respiration, generating energy in the form of ATP.1CoQ1 is an amphipathic CoQ10 homolog that has a tail consisting of five isoprene units. It has been used as an electron acceptor to study a range of oxidoreductases as isolated enzymes, in subcellular fractions, in intact cells in culture, and in perfused organs.2,3,4 Ubiquinone analogs, including CoQ1, impact mitochondrial permeability transition pore (PTP) formation, as well as PTP-dependent cell death, in an analog- and cell-specific manner.5 |
| 别名 | CoQ1;NSC 268269;Ubiquinone-1;Ubiquinone-5; |
| 供应商 | Cayman |
| 应用文献 | |
| 1.Crane, F.L. Biochemical functions of coenzyme Q10. Journal of the American College of Nutrition 20(6), 591-598 (2001). 2.Fato, R.,Estornell, E.,DiBernardo, S., et al. Steady-state kinetics of the reduction of coenzyme Q analogs by complex I (NADH:ubiquinone oxidoreductase) in bovine heart mitochondria and submitochondrial particles. Biochem. 35(8), 2705-2716 (1996). 3.Audi, S.H.,Merker, M.P.,Krenz, G.S., et al. Coenzyme Q1 redox metabolism during passage through the rat pulmonary circulation and the effect of hyperoxia. Journal of Applied Physiology 105(4), 1114-1126 (2008). 4.Bongard, R.D.,Myers, C.R.,Lindemer, B.J., et al. Coenzyme Q(1) as a probe for mitochondrial complex I activity in the intact perfused hyperoxia-exposed wild-type and Nqo1-null mouse lung. American Journal of Physiology.Lung Cellular and Molecular Physiology 302(9), L949-L958 (2012). 5.Devun, F.,Walter, L.,Belliere, J., et al. Ubiquinone analogs: A mitochondrial permeability transition pore-dependent pathway to selective cell death. PLoS One 5(7), (2010). | |
| 运输条件 | Room temperature in continental US; may vary elsewhere |
| 存放说明 | -20 |
| 纯度 | ≥98% |
| 计算分子量 | 250.3 |
| 分子式 | C14H18O4 |
| CAS号 | 727-81-1 |
| 稳定性 | ≥ 2 years |
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