(R)-Gyramide A (hydrochloride)
货号：
18528-1mg 基本售价：
490.0 元 规格：
1 mg
产品信息
概述| 货号 | 18528-1mg |
| 描述 | (R)-Gyramide A is a bacterial DNA gyrase inhibitor that disrupts supercoiling activity with an IC50 value of 3.3 µM.1 It does not affect the closely related enzyme topoisomerase IV.2 (R)-Gyramide A demonstrates antibacterial activity against E. coli,P. aeruginosa, and S. enterica (MICs range from 10-80 µM).1 |
| 别名 | (R)-534F6; |
性能| 供应商 | Cayman |
| 应用文献 |
1.Foss, M.H.,Hurley, K.A.,Sorto, N.A., et al. N-Benzyl-3-sulfonamidopyrrolidines are a new class of bacterial DNA gyrase inhibitors. ACS Med.Chem.Lett. 2, 289-292 (2011).
2.Rajendram, M.,Hurley, K.A.,Foss, M.H., et al. Gyramides prevent bacterial growth by inhibiting DNA gyrase and altering chromosome topology. ACS Chemical Biology 9(6), 1312-1319 (2014).
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| 运输条件 | Room temperature in continental US; may vary elsewhere |
| 存放说明 | -20 |
| 纯度 | ≥95% |
| 计算分子量 | 443 |
| 分子式 | C21H27FN2O3S • HCl |
| CAS号 | 1793050-70-0 |
| 稳定性 | ≥ 2 years |
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