Y11
货号：
18521-1mg 基本售价：
490.0 元 规格：
1 mg
产品信息
概述| 货号 | 18521-1mg |
| 描述 | Focal adhesion kinases (FAKs) are non-receptor tyrosine kinases that play roles in regulating diverse processes, including cell adhesion, spreading, migration, proliferation, and apoptosis. They are over-expressed in many types of cancer. Y11 inhibits FAK1 autophosphorylation by blocking phosphorylation of Y397.1 At 100 µM, it was shown to decrease cell viability of T47D breast cancer and C8161 melanoma cell lines.1 |
| 别名 | FAK Inhibitor 10;NSC 206142; |
性能| 供应商 | Cayman |
| 应用文献 |
1.Golubovskaya, V.M.,Nyberg, C.,Zheng, M., et al. A small molecule inhibitor, 1,2,4,5-benzenetetraamine tetrahydrochloride, targeting the Y397 site of focal adhesion kinase decreases tumor growth. Journal of Medicinal Chemistry 51(23), 7405-7416 (2008).
|
| 运输条件 | Room temperature in continental US; may vary elsewhere |
| 存放说明 | -20 |
| 纯度 | ≥95% |
| 计算分子量 | 265.2 |
| 分子式 | C8H17BrN4O |
| CAS号 | 1086639-59-9 |
| 稳定性 | ≥ 2 years |
声明| 本官网所有报价均为常温或者蓝冰运输价格，如有产品需要干冰运输，需另外加收干冰运输费。 |
