| 货号 | 18393-1mg |
| 描述 | Fexinidazole is an antiparasitic drug that, in different preparations, is effective against trypanosomes.1,2 It is orally available and rapidly metabolized to two active metabolites, a sulfone and a sulfoxide.2,3 Fexinidazole has been shown to kill both T. brucei gambiense andT. brucei rhodesiense in animal studies and is being tested for use in human African trypanosomiasis.4,3 |
| 供应商 | Cayman |
| 应用文献 | |
| 1.Jennings, F.W.,Atouguia, J.M., and Murray, M. Topical chemotherapy for experimental murine African CNS-trypanosomiasis: The successful use of the arsenical, melarsoprol, combined with the 5-nitroimidazoles, fexinidazole or MK-436. Trop.Med.Int.Health 1(5), 590-598 (1996). 2.Torreele, E.,Bourdin Trunz, B.,Tweats, D., et al. Fexinidazole--a new oral nitroimidazole drug candidate entering clinical development for the treatment of sleeping sickness. PLoS Negl.Trop.Dis. 4(12), (2010). 3.Eperon, G.,Balasegaram, M.,Potet, J., et al. Treatment options for second-stage gambiense human African trypanosomiasis. Expert Rev.Anti.Infect.Ther. 12(11), 1407-1417 (2014). 4.Steinmann, P.,Stone, C.M.,Sutherland, C.S., et al. Contemporary and emerging strategies for eliminating human African trypanosomiasis due to Trypanosoma brucei gambiense: Review. Trop.Med.Int.Health 20(6), 707-718 (2015). | |
| 运输条件 | Room temperature in continental US; may vary elsewhere |
| 存放说明 | -20 |
| 纯度 | ≥98% |
| 计算分子量 | 279.3 |
| 分子式 | C12H13N3O3S |
| CAS号 | 59729-37-2 |
| 稳定性 | ≥ 2 years |
| 本官网所有报价均为常温或者蓝冰运输价格，如有产品需要干冰运输，需另外加收干冰运输费。 |