NVP-ADW742
货号：
18390-1mg 基本售价：
490.0 元 规格：
1 mg
产品信息
概述| 货号 | 18390-1mg |
| 描述 | NVP-ADW742 is an insulin-like growth factor 1 receptor (IGF-1R) inhibitor with an IC50 value of 0.17 µM.1 It exhibits 6-fold greater selectivity for IGF-1R over the insulin receptor (InsR) kinase and minimal inhibitory activity against c-Kit, HER1, PDGFR, VEGFR2, or Bcr-Abl p210.1 NVP-ADW742 has been shown to inhibit tumor proliferation both in vitro and in a mouse model of multiple myeloma.1 |
| 别名 | ADW742;GSK552602A; |
性能| 供应商 | Cayman |
| 应用文献 |
1.Mitsiades, C.S.,Mitsiades, N.S.,McMullan, C.J., et al. Inhibition of the insulin-like growth factor receptor-1 tyrosine kinase activity as a therapeutic strategy for multiple myeloma, other hematologic malignancies, and solid tumors. Cancer Cell 5(3), 221-230 (2004).
|
| 运输条件 | Room temperature in continental US; may vary elsewhere |
| 存放说明 | -20 |
| 纯度 | ≥98% |
| 计算分子量 | 453.6 |
| 分子式 | C28H31N5O |
| CAS号 | 475488-23-4 |
| 稳定性 | ≥ 2 years |
声明| 本官网所有报价均为常温或者蓝冰运输价格，如有产品需要干冰运输，需另外加收干冰运输费。 |
